Peng Zhang, Ph. D.

ORCID: 0000-0003-0408-2923

ResearchGate: www.researchgate.net/profile/Peng-Zhang-33

 

Professional Experience

Oct.2010. - Present      Principle Investigator of Structural Biology, CAS Center for Excellence in Molecular Plant Sciences/Institute of Plant Physiology and Ecology,
Chinese Academy of Sciences. Shanghai, China.

Feb.2008. - Oct.2010.   Postdoctoral Research Associate in Lewis-Thomas Laboratory, Department of Molecular Biology, Princeton University; Princeton, New
Jersey, USA. Supervisor: Dr. Yigong Shi, Professor.

Jul.2007. - Jan.2008.     Research Assistant. Institute of Biochemistry and Cell Biology, SIBS, CAS. Shanghai, China.

Education

Sept.2002 - Jul.2007.     Ph.D. in Biochemistry and Molecular Biology. Institute of Biochemistry and Cell Biology (IBCB), SIBS, CAS. Shanghai, China. (Advisor: Dr. Jianping Ding, Professor.)

Sept.1998. - Jul.2002.     B.S. in Biochemistry and Molecular Biology. Shandong University. Jinan, China.

Honor and Awards

2021 CSPB outstanding young scientist, Chinese Society of Plant Biology (CSPB)
2020 National Natural Science Foundation for Outstanding Young Scholar, China.
2018 Newton advanced Fellowship, the Royal Society.

2013 National Natural Science Foundation for Excellent Young Scholar, China.
2012 Special talent of Shanghai Institutes for Biological Science, CAS.
2011 Shanghai Pujiang Talent programme, Shanghai

Selected publications:

1.    Zhang X.#, Carroll W.#, Nguyen T.B.#, Nguyen T.H., Yang Z., Ma M.L., Huang X.W., Hills A., Guo H., Karnik R., Blatt M.R.*, Zhang P. *.  GORK K+ channel structure and gating vital to informing stomatal engineering. Nat Commun. 2025. (accepted).
2.    Wang J.P.#, Du B.Y.#, Zhang X.#, Qu X.M., Yang Y., Yang Z., Wang Y.F.*, Zhang P.*. Cryo-EM structures of Arabidopsis CNGC1 and CNGC5 reveal molecular mechanisms underlying gating and calcium selectivity. Nat Plants. 2025b. doi:10.1038/s41477-025-01923-z
3.    Fang S.#, Yang Y.#, Zhang X.#, Yang Z., Zhang M.H., Zhao Y., Zhang C.S., Yu F., Wang Y.F.*, Zhang P.*. Structural mechanism underlying PHO1;H1 mediated phosphate transport in Arabidopsis. Nat Plants. 2025a. doi:10.1038/s41477-024-01895-6.
4.    An N.#, Huang X.W.#, Yang Z., Zhang M.H., Ma M.L., Yu Fang., Jing L.Y., Du B.Y., Wang Y.F., Zhang X.*, Zhang P.*. Cryo-EM structure and molecular mechanism of the jasmonic acid transporter ABCG16. Nat Plants. 2024. 10: 2052-2061. doi:10.1038/s41477-024-01839-0.
5.    Huang X.W.#, Zhang X.#, An N., Zhang M.H., Ma M.L., Yang Y., Jing L.Y., Wang Y.F., Chen Z.G.*, Zhang P.*. Cryo-EM structure and molecular mechanism of abscisic acid transporter ABCG25. Nat Plants. 2023.9(10):1709-1719. doi:10.1038/s41477-023-01509-7
6.    Yang Z.#, Zhang X.#, Ye S.W.#, Zheng J.T., Huang X.W., Yu F., Chen Z.G.*, Cai S.Q.*, Zhang P.*. Molecular mechanism underlying regulation of Arabidopsis CLCa transporter by nucleotides and phospholipids. Nat Commun. 2023. 14(1): 4879. doi: 10.1038/s41467-023-40624-z
7.    Ha Y.H. #, Zhang X. #, Liu Y.Q., Ma M.L., Huang X.W., Liu H.T., Zhang P.*. Cryo-EM structure of the CRY2 and CIB1 fragment complex provides insights into CIB1-mediated photosignaling. Plant Commun. 2023. 4(2):100475. doi: 10.1016/j.xplc.2022.100475.
8.    Fang S. #, Huang X.W.#, Zhang X.#,*, Zhang M.H., Hao YH, Guo H., Liu L.N., Yu F., Zhang P.*. Molecular mechanism underlying transport and allosteric inhibition of bicarbonate transporter SbtA. Proc Natl Acad Sci U S A. 2021.118 (22) e2101632118. doi: 10.1073/pnas.2101632118.
9.    Shao K. #, Zhang X. #, Li X. #, Hao Y.H., Huang X.W., Ma M.L., Zhang M.H., Yu F., Liu H.T.*, Zhang P.*. The oligomeric structures of plant cryptochromes. Nat. Struct. Mol. Biol. 2020. 27(5): 480-488. doi: 10.1038/s41594-020-0420-x.（Views and News in NSMB）
10.    Li J.X.#, Yu F. #, Guo H., Xiong R.X., Zhang W.J., He F.Y., Zhang M.H., Zhang P.*. Crystal structure of plant PLDα1 reveals catalytic and regulatory mechanisms of eukaryotic phospholipase D. Cell Res. 2020.30(1): 61-69. doi: 10.1038/s41422-019-0244-6.
11.    Wang C.C., Sun B., Zhang X., Huang X.W., Zhang M.H., Guo H., Chen X., Huang F., Chen T.Y., Mi H.L., Yu F., Liu L.N., Zhang P.*. Structural mechanism of the active bicarbonate transporter from cyanobacteria. Nat Plants. 2019. 5(11):1184-1193. doi: 10.1038/s41477-019-0538-1.
12.    Li J.X. #, Wang C.Y. # , Yang G.H., Sun Z., Guo H., Shao K., Gu Y., Jiang W.H.*, Zhang P.*. Molecular mechanism of environmental D-xylose perception by a XylFII-LytS complex in bacteria. Proc Natl Acad Sci U S A. 2017. 114(31):8235-8240. doi: 10.1073/pnas.1620183114.
13.    Bao Z.H. #, Qi X.F. #, Hong S., Xu K., He F.Y., Zhang M.H., Chen J.G., Chao D.Y., Zhao W., Li D.F., Wang JW. *, Zhang P.*. Structure and mechanism of a group‐I cobalt energy coupling factor transporter. Cell Res. 2017. 27(5):675-687. doi: 10.1038/cr.2017.38.
14.    Qi X.F., Lin W., Ma M.L., Wang C.Y., He Y., He N.S., Gao J., Zhou H., Xiao Y.L., Wang Y., and Zhang P.*. Structural basis of rifampin inactivation by rifampin phosphotransferase. Proc Natl Acad Sci U S A. 2016. 113 (14) 3803-3808. doi: 10.1073/pnas.1523614113.
15.    Wang C. #, Chen Q. #, Fan D., Li J., Wang G.*, and Zhang P.*. Structural analyses of short-chain prenyltransferases identify an evolutionarily conserved GFPPS clade in Brassicaceae plants. Mol Plant. 2016. 9(2):195-204. doi: 10.1016/j.molp.2015.10.010. (Cover & Highlight)
16.    Zhao Q. #, Wang C.C. #, Wang C.Y., Guo H., Bao Z.H., Zhang M.H., Zhang P.*. Structures of FolT at substrate-bound and substrate-released conformations reveal a gating mechanism of ECF transporters. Nat Commun. 2015. 6:7661. doi: 10.1038/ncomms8661.
17.     Yu F. #, He F.Y. #, Yao H.Y., Wang C.Y., Wang J.C., Li J.X., Qi X.F., Xue H.W.*, Ding J.P.*, Zhang P.*. Structural basis of intramitochondrial phosphatidic acid transport mediated by Ups1-Mdm35 complex. EMBO Rep. 2015. 16 (7). 813-823. doi: 10.15252/embr.201540137. (Recommended by Faculty 1000, Biology)
18.    Zhang M.H.#, Bao Z.H.#, Zhao Q., Guo H., Xu K., Wang C.C., Zhang P.*. Structure of a pantothenate transporter and implications for ECF module sharing and energy coupling of group II ECF transporters. Proc Natl Acad Sci U S A. 2014. 111(52):18560-18565. doi: 10.1073/pnas.1412246112.
19.    Xu K. #, Zhang M.H. #, Zhao Q. #, Yu F. #, Guo H., Wang C.Y., He F.Y., Ding J.P., Zhang P.*. Crystal structure of a folate energy-coupling factor transporter from Lactobacillus brevis. Nature. 2013. 497(7448):268-271. doi: 10.1038/nature12046. (Recommended by Faculty 1000, Biology; Highlighted by Nature China.)
20.    Zhang P., Wang J.W. and Shi Y. Structure and mechanism of the S component of a bacterial ECF transporter. Nature. 2010; 468(7324): 717-720. doi: 10.1038/nature09488. (Recommended by Faculty 1000, Biology)